When it comes to using and managing your medications, it is important to play an active role in your own healthcare. Because health risks accompany all medications, talk to your doctor or pharmacist about your medicines. According to the U.S. Food and Drug Administration (FDA), a drug is approved and considered safe enough when the benefits outweigh the known risks. To reduce risks and receive the most benefits, especially when taking multiple medications, the FDA encourages you to practice SAFER: